گزارش یک مورد: درمان جراحت عمیق در بند آخر انگشت رینگ با مرهم گیاهی

نویسندگان

1 دانشجوی پزشکی، کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی جهرم، جهرم، ایران

2 مرکز تحقیقات مولفه های اجتماعی نظام سلامت، دانشگاه علوم پزشکی جهرم، جهرم، ایران

3 بیوانفورماتیک، دانشگاه دی پاتیل هند، دانشکده مومبائی، هند

4 استادیار گروه ارتوپدی، دانشگاه علوم پزشکی جهرم،جهرم،ایران

چکیده

مقدمه: ترمیم و مراقبت از زخم ها که به دلیل سوختگی، دیابت، آسیب تروماتیک و همچنین جراحی ایجاد می شود، درصورت عدم درمان، خود یک تهدید جدی برای سلامتی محسوب می شوند.
معرفی بیمار: آقایی 18 ساله با شکایت از جراحت بند آخر انگشت رینگ دست چپ و خون ریزی فعال از محل جراحت به دنبال کار در کارگاه نجاری، به اورژانس بیمارستان مرودشت مراجعه کرده است. این بیمار پس از مراجعه به متخصص ارتوپدی و دریافت پیشنهاد انجام ترمیم بافت در اتاق عمل، از ادامه درمان منصرف شده و سعی در ترمیم بافت آسیب دیده خود به روش های سنتی می کند. داروی سنتی استفاده شده مشهور به اکسیر جامع شامل ترکیب زعفران و عسل برای کاهش عفونت، ترکیب هل، خربق سفید و بنج برای التیام و فلفل سفید به عنوان مسکن بوده است.
نتیجه گیری: نتایج این مطالعه نشان داد که ترکیب داروی اکسیر جامع منجر به بهبودی جراحت مذکور می شود. این چنین زخم ها به دلیل خطر ابتلا به استئومیلیت نیاز به مصرف آنتی بیوتیک دارند. بنابراین، استفاده موضعی این ترکیب گیاهی هم خاصیت آنتی بیوتیکی و هم خاصیت ترمیمی داشته است.

کلیدواژه‌ها

عنوان مقاله [English]

Case Report: Treatment of a Patient with Deep Injury in the Last Finger of the Ring with Herbal Ointment

نویسندگان [English]

  • Alireza Hashemi 1
  • Navid Kalani 2
  • Mohammad mazaher Bojani 3
  • Masomeh Pourmokhtari 4

1 Student research committee, Jahrom university of medical sciences, Jahrom, Iran

2 Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran

3 BSc in Bioinformatics, De Patil University of India, Mumbai School, India

4 Assistant Professor of Orthopedics, Jahrom University of Medical Sciences, Jahrom, Iran

چکیده [English]

Introduction: Wound healing, which is caused by burns, diabetes, traumatic injury, as well as surgery, poses a serious
health threat if left untreated.
Case Report: The patient is an 18-year-old man with a complaint of injury to the last finger ring of the left hand and
active bleeding from the site of the injury following work in a carpentry workshop, referred to the emergency department of Marvdasht Hospital. After referring to an orthopedic specialist and suggesting tissue repair in the operating room by the doctor, this patient refuses to continue treatment and tries to repair the damaged tissue by traditional methods. The compounds used by a person who masters the rules of traditional Iranian medicine are known as a comprehensive elixir and include a combination of saffron and honey to reduce infection, and a combination of cardamom, white fennel and ginger for healing and a combination of white pepper as a painkiller.
Conclusion: The results of this study showed that the combination of herbs with a comprehensive elixir could heal the injury. Such wounds require the use of antibiotics due to the risk of osteomyelitis. Therefore, topical application of this herbal compound has shown both antibiotic and restorative properties

کلیدواژه‌ها [English]

  • Finger Injuries
  • Zone1
  • Comprehensive Elixir Herbal Supplement
  • Saffron
  • Fenugreek
  • Cardamom
  • Lavender
  • White Pepper
  • Banj
  • Aqr Qarha
  • Honey
1.Beers EH. Palliative Wound Care: Less Is More. SurgClin North Am. 2019;99(5):899-919.2.Childs DR, Murthy AS. Overview of Wound Healingand Management. Surg Clin North Am.2017;97(1):189-207.
3.Fitridge R, Thompson M. Mechanisms of vasculardisease :a reference book for vascular specialists:University of Adelaide Press; 2011.4.Landen NX, Li D, Stahle M. Transition frominflammation to proliferation: a critical step during
wound healing. Cell Mol Life Sci. 2016;73(20):3861-85.5.Negut I, Grumezescu V, Grumezescu AM. Treatment
Strategies for Infected Wounds. Molecules.2018;23 (9.)6.Jarbrink K, Ni G, Sonnergren H, Schmidtchen A,
Pang C, Bajpai R, et al. The humanistic and economicburden of chronic wounds: a protocol for a systematicreview. Syst Rev. 2017;6(1):15.7.Larouche J, Sheoran S, Maruyama K, Martino MM.Immune Regulation of Skin Wound Healing:Mechanisms and Novel Therapeutic Targets. AdvWound Care (New Rochelle). 2018;7(7):209-31.8.Ramponi DR, Ramirez EG, Hoyt KS. Management ofhand injuries: Part II. Advanced emergency nursingjournal. 2016;38(4):266-78.9.Satku M, Puhaindran ME, Chong AKS.Characteristics of fingertip injuries in children inSingapore. Hand surgery. 2015;20(03):410-4.10.Johnson BA, Wang QC. Fingertip injuries .Americanfamily physician. 2001;63(10):1961.11.Rosenthal E. Treatment of fingertip and nail bed
injuries. The Orthopedic clinics of North America.1983;14(4):675-97.12.Lister G. The hand: diagnosis and indications. The
hand: diagnosis and indications1993. p. 503 -.13.Jackson E. The VY plasty in the treatment offingertip amputations. American family physician.2001;64(3):455.14.Figueiredo LAd, Ribeiro RdS, Melo ALBd, LimaAL, Terra BB, Ventim FC. Polypropylene prosthesisfor the treatment of fingertip injuries. Description ofsurgical technique and results. Revista brasileira deortopedia. 2017;52(6):685-92.15.Dreifke MB, Jayasuriya AA, Jayasuriya AC. Currentwound healing procedures and potential care. MaterSci Eng C Mater Biol Appl. 2015;48 :156-16.16.Lomovskaya O, Warren MS, Lee A, Galazzo J,
Fronko R, Lee M, et al. Identification andcharacterization of inhibitors of multidrug resistanceefflux pumps in Pseudomonas aeruginosa: novelagents for combination therapy. Antimicrobial agentsand chemotherapy. 2001;45(1):105-16.17.Mangram A. A brief overview of the 1999 CDCGuideline for the Prevention of Surgical Site
Infection. Journal of Chemotherapy. 2001;13(sup4):35-9.18.Dorai AA. Wound care with traditional,complementary and alternative medicine. Indian JPlast Surg. 2012;45(2):418-24.19.Martins M, McCusker MP, Viveiros M, Couto I,Fanning S, Pagès J-M, et al. A simple method forassessment of MDR bacteria for over-expressed effluxpumps. The open microbiology journal. 2013;7:72.20.Zeka K, Ruparelia KC, Sansone C, Macchiarelli G,Continenza MA, Arroo RRJ. New HydrogelsEnriched with Antioxidants from Saffron Crocus CanFind Applications in Wound Treatment and/orBeautification. Skin Pharmacol Physiol.2018;31(2):95-8.21.Teb Entezaei Book. Volume 1, P: 315-316.
22.History of Islamic Culture and Civilization (formedical sciences), P: 170.23.Bang JS, Oh DH, Choi HM, Sur BJ, Lim SJ, Kim JY,et al. Anti-inflammatory and antiarthritic effects ofpiperine in human interleukin 1beta-stimulatedfibroblast-like synoviocytes and in rat arthritismodels. Arthritis Res Ther. 2009;11(2):R49.24.Bhardwaj RK, Glaeser H, Becquemont L, Klotz U,Gupta SK, Fromm MF. Piperine, a major constituentof black pepper, inhibits human P-glycoprotein andCYP3A4 .J Pharmacol Exp Ther. 2002;302(2):645-50.25.Kholasetol hekmat book, Volume 3, P: 122.26.Gharabadin kabir book. Volume 1, P: 695.27.Dictionary Tebe eslami, Volume 4, P: 434.28.Zechini B, Versace I. Inhibitors of multidrugresistant efflux systems in bacteria. Recent patents onanti-infective drug discovery. 2009;4(1):37-50.29.Teb Entezaei Books. Volume 1, P: 468.
30.Maaref Giahi, Volume 2, P: 441.31.Bogucka-Kocka A, Smolarz H, Kocki J. Apoptoticactivities of ethanol extracts from some Apiaceae onhuman leukaemia cell lines. Fitoterapia. 2008;79(7-8):487-97.32.Debnath B, Singh WS, Das M, Goswami S, SinghMK, Maiti D, et al. Role of plant alkaloids on humanhealth: A review of biological activities. MaterialsToday Chemistry. 2018;9:56-72.33.Dumlu FA, Aydin T, Odabasoglu F, Berktas OA,Kutlu Z, Erol HS, et al. Anti-inflammatory and
antioxidant properties of jervine, a sterodial alkaloidfrom rhizomes of Veratrum album. Phytomedicine.2019;55:191-9.
34.Molyneux RJ, Lee ST, Gardner DR, Panter KE,James LF. Phytochemicals: the good, the bad and theugly? Phytochemistry. 2007;68(22-24):2973-85.35.Maaref Giahi, Volume 4, P: 147.36.Dictionary Tebe eslami, Volume 2, P: 430-431.
37.Secrets of medicinal plants, P: 467.38.Nuutinen T. Medicinal properties of terpenes found
in Cannabis sativa and Humulus lupulus. Eur J MedChem. 2018;157:198-228.39.Secrets of medicinal plants, P: 206.
40.Dictionary of Iranian Herbal Medicine, P: 916.41.Veryser L, Taevernier L, Roche N, Peremans K,
Burvenich C, De Spiegeleer B. Quantitativetransdermal behavior of pellitorine from Anacycluspyrethrum extract. Phytomedicine. 2014;21(14):1801-7.42.Zhakhireh Kharazmshahi book, Volume 9, P: 246.43.Tohfatol Momenin book, Volume 2, P: 149.44.Nam SM, Choi JH, Yoo DY, Kim W, Jung HY, KimJW, et al. Valeriana officinalis extract and its maincomponent, valerenic acid, ameliorate D-galactose-induced reductions in memory, cell proliferation, and
neuroblast differentiation by reducing corticosteronelevels and lipid peroxidation. Exp Gerontol.
2013;48(11):1369-77.45.Makhzanel advieh: Dictionary of Iranian TraditionalMedicine Foods and Medicines, P: 524.
46.Yaghoobi R, Kazerouni A, kazerouni O. Evidencefor Clinical Use of Honey in Wound Healing as an
Anti-bacterial, Anti-inflammatory Anti-oxidant andAnti-viral Agent. Jundishapur Journal of Natural
Pharmaceutical Products. 2013.47.Al-Waili NS. Topical honey application vs. acyclovirfor the treatment of recurrent herpes simplex lesions.Medical Science Monitor. 2004