مجله علوم پزشکی پارس

اثر یک دوره تمرین مقاومتی دایره ای به همراه عصاره یونجه بر سطوح استئوپروتگرین و فاکتور هسته ای کاپا بی در دختران لاغر

نویسندگان

1 دانشگاه آزاد اسلامی ساری

2 دانشگاه آزادساری

3 دانشگاه آزاد

چکیده

چکیده

 مقدمه: پوکی استخوان رایج ترین بیماری متابولیکی استخوان است که عوامل مختلفی مانند شاخص پایین توده بدن و عدم فعالیت جسمانی در بروز این بیماری دخالت دارند. تعدیل شیوه زندگی می تواند یک استراتژی مفید برای پیش گیری از این بیماری باشد. لذا هدف مطالعه حاضر تعیین اثر تمرین مقاومتی دایره ای و مصرف عصاره یونجه بر سطوح استئوپروتگرین و فاکتور هسته ای کاپا بی  در دختران جوان لاغر بود.

روش کار: در این مطالعه نیمه تجربی 28 نفر از دختران  دانش‌آموز (16 تا 19 سال) بطور تصادفی و مساوی به چهار گروه (مکمل، تمرین، تمرین- مکمل و کنترل) تقسیم شدند. برنامه تمرین مقاومتی شامل 10 حرکت با شدت 60 تا 80 درصد یک تکرار بیشینه بود که در 8 الی 12 تکرار، طی 4 هفته، سه جلسه/ هفته 60 دقیقه/ جلسه انجام شد. مکمل یونجه به میزان یک سی سی/ کیلوگرم وزن بدن، هر 3 بار در روز و به مدت 4 هفته مصرف  شد. آنالیز داده ها با استفاده از آزمون های t زوجی  و آنالیز واریانس یک راهه انجام شد(05/0P<).

یافته ها:  4 هفته تمرین مقاومتی دایره ای، مکمل سازی و مداخله ترکیبی با افزایش معنی دار سطوح استئوپروتگرین و کاهش معنی دار سطوح فاکتور هسته ای کاپا بی دردختران لاغر همراه بود(05/0>p < /span>). بعلاوه مداخله ترکیبی با تغییر بیشتری در سطوح این شاخص ها در مقایسه با گروه  تمرین و مکمل همراه بود(05/0>p < /span>).

نتیجه گیری: انجام تمرینات مقاومتی دایره ای و مصرف عصاره یونجه به عنوان یک روش درمانی غیر دارویی می تواند سبب افزایش شاخص های تشکیل استخوان و نیز کاهش فعالیت مسیر تحلیل آن در دختران جوان لاغر گردد، البته اثر بخشی ترکیب تمرین و مکمل  بیشتر از اثرات جداگانه هر یک از مداخله  ها می باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The Effect of resistance training circuit with Medicago sativa extracts on levels of Osteoprotegerin and Nuclear Factor of Kappa-B in thin girls

نویسندگان [English]

  • parvin farzanegi 1
  • khatereh ebrahimi 2
  • masoumeh habibian 3

1

2

3

چکیده [English]

Abstract

Introduction:

 Osteoporosis is the most common metabolic bone disease with high prevalence that various factors are involved in the pathogenesis of this disease, including the low body mass index and lack of physical activity. Change in lifestyle represents a successful strategy to prevent future disease. Therefore the aim of this study was determine the interactive effects of resistance training and Medicago sativa extracts consumption on serum level of steoprotegerin and nuclear factor kappa B in thin girls.

Materials and Methods:

In one Quasi-experimental study, 28 female students (16 to 19 years) divided into 4 groups, including: supplement, training , training-supplement and Control randomly. Resistance training program consisted of 10 exercise movements at 60-80% of one repeated maximal in 8-12 repetition (in 3 circuits), 60 min per day and 3 sessions per week for 4 weeks. Intake Medicago sativa supplement was 1 ml/kg body weight for 3 times a day. Data were analyzed with Paired t and ANOVA tests ( P<0.05) .

Results:

Four weeks of resistance training, supplementation and the combined intervention were associated with a significant increase in steoprotegerin and  decrease in nuclear factor kappa B levels (P<0/05) in thin girls. Furthermore combined intervention were associated with greater changes in percent changes of these inducator compare training and supplement groups (p<0.05).

Conclusion:

Regular resistance training with consumption of Medicago sativa extracts as a non-drug therapy can increase bone formation markers and also reduce the activity of the absorbency pathway in thin adolescent girls. Of course the combination of exercise and supplement are more effective than the separate effects of each them.

کلیدواژه‌ها [English]

  • resistance training
  • Medicago sativa
  • steoprotegerin
  • nuclear factor kappa B
  • thinness
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مجله علوم پزشکی پارس
دوره 14، شماره 3 - شماره پیاپی 37
مهر 1395
صفحه 27-34