بررسی سرولوژی توکسوپلاسموز در زنان باردار شهرستان جهرم، 1397

نویسندگان

1 گروه انگل شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی جهرم، جهرم، ایران

2 مرکز تحقیقات زئونوز،دانشگاه علوم پزشکی جهرم، جهرم، ایران

چکیده

مقدمه: توکسوپلاسموزیس یکی از شایع ترین بیماری های عفونی در جهان است که توسط انگل توکسوپلاسما گوندی ایجاد می شود. انتقال این انگل از مادر به جنین در دوران بارداری ممکن است به عوارض کلینیکی مختلفی همچون سقط جنین یا عوارض مغزی و چشمی در نوزادان منجر شود. این مطالعه با هدف تعیین فراوانی آنتی بادی های ضد توکسوپلاسما در زنان باردار جهرم انجام شد.
روش کار: در این مطالعه توصیفی- مقطعی از 370 زن باردار که در سه ماهه اول بارداری بودند نمونه خونی گرفته شد. همزمان با نمونه گیری، داده های مربوط به ویژگی های اجتماعی و جمعیت شناختی شرکت کنندگان ثبت شد. سپس سرم ها از نظر وجود
آنتی بادی های IgG و IgM علیه توکسوپلاسما گوندی به روش الیزا  بررسی شدند. داده های به دست آمده با استفاده از نرم افزار SPSS  مورد تحلیل آماری قرار گرفتند.
یافته ها: IgG و IgM ضد توکسوپلاسما به ترتیب در ۱۰۹ (29.5  درصد) و 2 (0.5 درصد) زن باردار مشاهده شد. بین آلودگی با سن، میزان تحصیلات، محل زندگی، شغل، نوع آب آشامیدنی مصرفی، تماس با گربه، سابقه سقط جنین و سابقه تولد نوزاد ناهنجار ارتباط معناداری مشاهده نشد (P>0.05)، اما ارتباط آلودگی با تعداد فرزندان معنادار بود (P=0.005).
نتیجه گیری: با توجه به نتایج، 70.5 درصد از زنان باردار آنتی ­بادی ضد توکسوپلاسما در سرم نداشتند و در مقابل آلودگی به توکسوپلاسما مصون نبودند. بنابراین راهنمایی های پیشگیری از عفونت توکسوپلاسما باید در برنامه های آموزشی زنان باردار گنجانده شود.

کلیدواژه‌ها

عنوان مقاله [English]

Serological study of toxoplasmosis in pregnant women in Jahrom city, 2018

نویسندگان [English]

  • Salar Maani 1
  • Mojtaba Kazemi 1
  • Kavos Solhjoo 1
  • Enayatollah Shadmand 1
  • Hassan Rezanezhad 2

1 Parasitology Dept, Jahrom University of Medical Sciences, Jahrom, Iran

2 Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran

چکیده [English]

Introduction: Toxoplasmosis is one of the most common infectious diseases in the world caused by Toxoplasma gondii. Transmission of the parasite from mother to fetus during pregnancy, may lead to important clinical complications such as abortion or cerebral and ocular damages in neonatal. This study aimed to determine the prevalence of antibodies against T. gondii in the pregnant women in Jahrom.
Materials & Methods: In this cross-sectional study, blood samples were collected from 370 pregnant women who were in the first trimester of pregnancy. Data on socio-demographic characteristics of the participants were recorded simultaneously with sampling. Then, the sera were examined for the presence of IgG and IgM antibodies against T. gondii using the ELISA method. The results were statistically analyzed using SPSS v.16.
Results: Anti-T. gondii IgG and IgM were detected in 109 (29.5%) and 2 (0.5%) pregnant women, respectively. There was no significant correlation between infection and age, education, place of residence, occupation, type of drinking water consumed, contact with cats, history of abortion, or history of abnormal birth (P> 0.05) but the association between infection and number of offspring was significant (P=0.005).
Conclusion: According to the results, 70.5% of pregnant women had no anti-Toxoplasma antibody in the serum and
they were not immune to Toxoplasma. Therefore, guidelines for the prevention of Toxoplasma infection should be incorporated into educational programs for the pregnant women.

کلیدواژه‌ها [English]

  • Toxoplasmosis
  • Serology
  • IgG
  • IgM
  • Pregnant Women
  • Jahrom
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