اثرات درمانی مداخله هوازی بر شاخص های واگردش استخوان در مردان سیگاری غیرفعال

نویسندگان

گروه فیزیولوژی ورزشی، دانشگاه آزاد اسلامی واحد ساوه، ساوه، ایران

چکیده

مقدمه: آلکالین فسفاتاز و استئوکلسین از شاخص های واگردش استخوان هستند به گونه ای که افزایش سطوح آنها با افزایش فرآیند تشکیل استخوان همراهند. از طرفی، استعمال مداوم سیگار با تغییر در شاخص های واگردش همراه است. مطالعه حاضر با هدف تعیین اثر 3 ماه تمرین هوازی بر آلکالین فسفاتاز و استئوکلسین به عنوان شاخص واگردش استخوان در مردان سیگاری انجام گرفت.
روش کار: 32 مرد سیگاری غیرفعال کم تحرک (2 ± 42 سال) در قالب نمونه گیری در دسترس جهت شرکت در مطالعه فرا خوانده شدند و به شیوه تصادفی به دو گروه تجربی (16=n) و کنترل (16=n) تقسیم شدند. گروه تجربی یک دوره تمرینات هوازی 3 ماهه (3 جلسه در هفته در دامنه 60 تا 80 درصد ضربان قلب بیشینه) را اجرا نمودند و گروه کنترل تمرین نداشتند. شاخص های آنتروپومتریکی، سطوح سرمی استئوکلسین و آلکالین فسفاتاز ناشتا در دو شرایط قبل و پس از برنامه تمرینی در هر دو گروه اندازه گیری شد. از آزمون آماری آنکوا برای ارزیابی سطح معنی داری تغییرات استفاده شد. تغییرات کمتر از 5 درصد معنی دار در نظر گرفته شد.  
یافته ها: کاهش معنی داری در شاخص های آنتروپومتریکی توسط تمرینات هوازی در گروه تجربی مشاهده شد (05/0>p < /span>). تمرین هوازی به افزایش معنی دار استئوکلسین سرم (011/0=p < /span>) و آلکالین فسفاتاز (019/0=p < /span>) در گروه تجربی منجر شد اما این متغیرها در گروه کنتل تغییر نکردند(05/0<p < /span>).
نتیجه گیری: تمرینات هوازی طولانی مدت در حضور تداوم مصرف سیگار به بهبود تشکیل استخوان در مردان سیگاری منجر می شود.
 

کلیدواژه‌ها

عنوان مقاله [English]

Therapeutic effect of aerobic training on bone remodeling markers in sedentary cigarette males

نویسندگان [English]

  • Davod Khorshidi
  • Mojtaba Eizadi

چکیده [English]

Introduction: Alkaline phosphatase and osteocalcin are bone remodeling markers. So that, increased their level is associated with bone formation. On the other hand, continued cigarette smoke is associated with the change in bone remodeling indexes. The present study aimed to assess the effect of 3 months aerobic training on alkaline phosphatase (ALP) and osteocalcin as bone remodeling markers in smoker males.
Materials and Method: Thirty two sedentary age-matched (42 ± 2 years of old) males’ cigarette smokers were recruited in this study by accessible sampling and were randomly divided into experimental (n = 16) and control (n = 16) groups. The experimental group performed 12 weeks of aerobic exercise (3 days per week / 60-80 % of maximum heart rate) and control subjects did not exercise training. Pre and post training of anthropometrical markers, fating serum osteocalcin and ALP were measured in 2 groups. The ANKOVA test was used to evaluate the statistical significance of the changes. The change less than 0.05 were considered significant. 
Results: Significant decreases were observed in anthropometrical markers by aerobic training in exercise group (p < 0.05). Aerobic training induced significant increase in serum osteocalcin (p = 0.011) and ALP (p = 0.019) in experimental group, but these variables did not change in control group (p > 0.05)
Conclusion: long term aerobic training in presence continued cigarette smoking can be improved bone formation in smoker males.
 

کلیدواژه‌ها [English]

  • Aerobic training
  • bone remodeling
  • cigarette
  • osteoporosis
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