Comparison of blood sugar fluctuations in non-diabetic patients during orthopedic surgery in general anesthesia and spinal anesthesia


1 Assistant Professor of Endocrinology & Metabolism, Jahrom University of Medical Sciences, Iran, Iran

2 Associate Professor of Anesthesiology, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran

3 Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran.

4 Associate Professor of Anesthesiology, Jahrom University of Medical Sciences, Iran, Iran

5 Research center for social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran


Introduction: One of the metabolic responses to surgical stress is changes in serum glucose levels of patients undergoing surgery. Therefore, the aim of this study was to compare the blood sugar fluctuations of non-diabetic patients during orthopedic surgery in general anesthesia and spinal anesthesia.
Materials and Methods: In this cohort study, 60 patients with anesthesia classes 1 and 2 underwent orthopedic surgery under general anesthesia and spinal anesthesia. Patients were divided into 2 groups: general anesthesia and spinal anesthesia. A glucometer was used to measure patients' blood sugar. Hemodynamic symptoms and chills were also assessed.
Results: Mean BS showed no significant difference between spinal anesthesia and general anesthesia groups in preoperative times, after spinal anesthesia or general anesthesia, at 30 minutes and 60 minutes postoperatively and in recovery (p> 0.05). Intra-group comparisons with analysis of variance with repeated measures showed that the mean trend of BS at the time of the study was significant only in the spinal anesthesia group (p = 0.006). The mean trend of BS in the spinal anesthesia group was reduced in the postoperative period compared to the preoperative period.
Conclusion: Considering the importance of regulating blood sugar around surgery, the present study preferred spinal
anesthesia to control the patient's blood sugar to some extent over general anesthesia; but confirmation of this finding requires more detailed studies.


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