Changes in Biochemical Parameters Following Exchange Transfusion
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Abstract
Introduction:In attention to high prevalence of ieter so Exchange transfusion as a therapeutic treatment ,this study was performed to determine the effects of exchange transfusion on biochemical parameters in newborns.
Methods: One hundred full term newborns who needed exchange transfusion were studied. Blood samples were collected before and after exchange transfusion. They were divided into two groups based on infusion of calcium gluconate or not received the drug during exchange transfusion.
Results: Significant increase in serum sodium and glucose level were observed but was not significant for potassium. A decrease in serum bilirubin was seen effect of transtuslon on serum bilirubia consist of a bone 65% decrees and then with a 31% rise after 4 hours. No significant difference was observed in serum calcium level between two groups but 20% of newborns presented hypocalcaemia symptoms.
Conclusion: Exchange transfusion can affect biochemical parameters in newborns that must be considered specially in sick infants. Calcium administration during exchange transfusion due to risk of hypocalcaemia is recommended.
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