Comparison of Nerve Conduction Velocity (NCV) In Chronic Renal Failure & Transplanted patients

Authors

Abstract

Peripheral neuropathy in chronic renal failure is reported. In this study NCV was

tested in chronic renal failure patients and those with renal transplantation.

Materials & methods:

A total of 33 patients in two groups were selected. Group I Consisted of 17 Patients

with CRF on hemodialysis (aged 19-60 years), Group II included 16 patiemts who

had successful renal transplantation. (aged 19-57 years). We studied motor & sensory

NCV after ruling out diabetes.

Results:

Motor NCV abnormality was seen in 41% of hemodialysed Patients & sensory NCV

abnormality is seen in 53%, while such abnormality was not observed in 16

transplanted patients.

Average motor NCV (Peroneal & median nerves) in group I was 44.7 ± 3.47 m/s & in

group II it was 50.1 ± 2.6 m/s. (P<0.01). Mean average sensony NCV in group I was

41.2 ± 4.49 m/s & in group II 49.1 ± 2.2 m/s This differences was significant (P<0.01).

Conclusion:

Delayed neural conduction in peripheral nerves is seen in patients with chronic renal

failure, that can be improved after successful renal tarns plantation. Etiologic factors

associated with abnormality might be circulating Toxins or demyelination

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