Manifestations, Complications and Underlying Disease Associated with Zona in Al_Zahra Hospital , Isfahan(1375-1385)

Introduction: Zona is a disease occurring  due to reactivation of dormant Herpes Zoster virus in the dorsal root gangelion and manifesting by vesicular rash in one dermatom. In old patients with underlying disease it is severe and has more complications.

Methods: In this criss-sectional and descriptive study 100 patients diagnosed with zona were reviewed in Al- Zahra hospital in Isfahan.  The patients were divided into three age groups . under 20 year old, 20through50years and above 50 years old information such as sex prevalence, underlying disease, the involved dermatome and complications were gathered. The data were analyzed using spss statistical package ,version 13.

Result: 1% of the patients were under 20 years, 16% between 20 and 50 years and %83 over  than 50 years old. 45%of the Cases were male and 55 %were female.Their Mean age was 61.4 ± 2. of 100 patients 68 cases had underlying disease. 23 cases a history of surgery in  the last two months.  (52/2% male, 47/8% female), and 15 cases diabetese  type II (46/7% male and 53/3% female). 13 cases had malignancy (69/2% male, 30/8% female), 13 cases had used corticostroid (46/2% male and 53/8% female) and 4 cases had psychological disorder that all were female. The most involved dermatom in the patients was 34 trigeminal, 24 thoracic, 7 cervical, 16 lumber, 12 sacral and 7 generalized. There was significant relation between underlying disease and the involved dermatom (P<0.001). All of the patients with generalized dermatom were immunocompromised.

Conclusion:  Zona is more common and severe in  the immunocompromised patients and people suffering from underlying disease. Therefore, this necessitates prevention of disseminated forms and complications of the disease through increasing  the patients,awareness in this regard and earlier presentation for treatment.