Introduction: The most common determinant for hydatidosis in human population is annually confirmed or surgical cases, but these are only a few parts of infected cases. Hydatidosis is one of the important of health problems in Iran, therefore seroepidemiological studies of hydatidosis can be an essential step to promotion of social health and prevention of this disease by determination of positive cases.

Materials and methods: In this descriptive-cross-sectional study, 1096 sera were randomly collected from persons referred to clinical laboratory in Jahrom from 2006 until 2007 and tested by ELISA for IgG against Ecchinococcus granulosus. While sampling, demographical features of these persons were recorded and the results analyzed by SPSS.

Results: Anti-Ecchinococcus granulosus IgG was detected in 69 (6.3%) of 1096 sera including 45 (65.2%) male, 24 (34.8%) female. The prevalence was higher in 46-60 years, age group, 21 cases (5.7%) than others. Seropositivity percent in rural and urban areas were 7.54% and 5.24% respectively. There was not significantly between seropositivity of hydatid cyst and variables such as gender, age groups and habitant (P>0.05).

Conclusions: The results showed that the seroprevalence of hydatidosis was 6.3% in Jahrom. There was higher seropositivity in rural area than urban area but there was not significantly between seropositivity of hydatid cyst and habitant.