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:: Volume 18, Issue 4 (winter 2020) ::
jmj 2020, 18(4): 9-16 Back to browse issues page
The effect of fentanyl addition to bupivacaine on shivering and vomiting nausea in patients undergoing femoral fracture surgery by spinal anesthesia: A double-blind randomized clinical trial
Javad Vagharfard , Ahmad Rastgarian , Mohammad Rahmanian , Masomeh Pourmokhtari , Mohammad hasan Damshenas , Samira Taban , Hasan Zabetian * , Navid Kalani , Naser Hatami
Abstract:   (434 Views)
Introduction: One of the most common complications after intrathecal anesthesia is chills during surgery. The second most common complaint followed by intrathecal anesthesia is nausea and vomiting. The aim of this study was to evaluate the effect of adding fentanyl to bupivacaine on chills and vomiting nausea in patients undergoing femoral surgery
Methods: This randomized double-blind clinical trial study was performed on 40 patients aged 18 to 50 years with anesthesia classes 1 and 2 who were candidates for femoral orthopedic surgery. Patients were randomly divided into two equal groups. The intervention group received 12.5 mg bupivacaine (2.5 cc) and 10 mg fentanyl (control group) and the control group received 12.5 μg bupivacaine (0.5 ml normal). Patients with dry mouth, nausea, vomiting and shivering were evaluated at 1, 2, 6, 12 and 24 hours after surgery. Data analysis was performed using SPSS software version 21 and descriptive and inferential statistical tests.
Results: Forty patients undergoing spinal orthopedic surgery with spinal anesthesia participated in two equal groups (bupivacaine-fentanyl (n = 20) and bupivacaine (n = 20). There was no significant difference between fentanyl and bupivacaine in terms of recovery from nausea and postoperative times (p> 0.05) and differences between bupivacaine-fentanyl and bupivacaine in shivering at 6, 12, 18 and 24 hours postoperatively. There was no significant (p> 0.05).
Conclusion: In the present study, although fewer complications such as shivering and nausea and vomiting were reported within minutes of the study in the fentanyl group, this decrease was not statistically significant.
Keywords: Bupivacaine, Fentanyl, Spinal Anesthesia, Shivering, Vomiting Nausea, Femoral Fracture.
Full-Text [PDF 747 kb]   (139 Downloads)    
Type of Study: Research | Subject: bihosh
Received: 2020/12/7 | Revised: 2021/07/25 | Accepted: 2021/02/13
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Research code: 1399.011
Ethics code: IR.JUMS.REC.1399.011
Clinical trials code: IRCT20130926014779N4


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vagharfard J, rastgarian A, Rahmanian M, pourmokhtari M, damshenas M H, taban S, et al . The effect of fentanyl addition to bupivacaine on shivering and vomiting nausea in patients undergoing femoral fracture surgery by spinal anesthesia: A double-blind randomized clinical trial. jmj. 2020; 18 (4) :9-16
URL: http://jmj.jums.ac.ir/article-1-1556-en.html


Volume 18, Issue 4 (winter 2020) Back to browse issues page
فصلنامه دانشگاه علوم پزشکی جهرم Journal of Jahrom University of Medical Sciences
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