:: Volume 18, Issue 2 (summer 2020) ::
jmj 2020, 18(2): 49-56 Back to browse issues page
The survey of effectiveness of Regular Exercise Training on Fetuin-A and Adiponectin Levels in overweight Postmenopausal Women with Type 2 Diabetes Mellitus
Faremeh Abbaszadeh Talarposhti
Abstract:   (1538 Views)
 Higher levels of fetuin-A and hypoadiponectinemia are associated with impaired glucose regulation and pathogenesis of type 2 diabetes. The aim of this study was to the survey of   effectiveness of Regular Exercise training on Fetuin-A and Adiponectin levels in overweight postmenopausal women with type 2 diabetes mellitus(T2DM).
Materials & Methods:
  This semi experimental research, twenty sedentary overweight postmenopausal women with T2DM were selected through convenience sampling and then randomly divided into control and exercise groups (n=10). Training program consisted of 25-40 minutes of aerobic exercise at 50-70 percent of maximal heart rate, 3 sessions per week for 8 weeks. The plasma levels of Fetuin-A and Adiponectin using ELISA method and glucose levels via enzymatic colorimetric method were measured. Data were analyzed by paired and independent t tests. The level of statistical significance was set at P< 0.05.
Findings:
Based on the results, 8 weeks of aerobic exercise were associated with decreased glucose levels (P = 0.002), Fetuin-A (P = 0.001) and body weight (P = 0.001), and also increased adiponectin (P <0.001) in the trained group compared to the control group.
Conclusion:
It seems that regular aerobic exercise can mediate some of its beneficial effects in the pathological conditions of type 2 diabetes by lowering plasma levels of Fetuin-A and up-regulating adiponectin.
Keywords: Adiponectin, Exercise Trainig, Fetuin-A, Type 2 Diabetes
Full-Text [PDF 819 kb]   (373 Downloads)    
Type of Study: Research | Subject: Physiology varzeshi
Received: 2021/02/19 | Revised: 2021/05/22 | Accepted: 2020/09/5



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Volume 18, Issue 2 (summer 2020) Back to browse issues page