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:: Volume 19, Issue 3 (fall 2021) ::
jmj 2021, 19(3): 39-44 Back to browse issues page
Seroloprevalence of Hepatits G Virus (HGV) in Thalassemia Patients Jahrom-Iran, 1399
Masihollah Shakeri , Karamatollah Rahmanian , Sotoodeh jahromi , Abdolreza Sotoodeh jahromi *
Jahrom University of medical sciences, Jahrom, Iran
Abstract:   (1777 Views)
Introduction:
People who have multiple transfusions, such as Beta-thalassemia patients, are at risk for the hepatitis G virus (HGV) infection. The aim of the study was the determination of serological prevalence of HGV and its associated factors in beta-thalassemia major patients in Jahrom-Iran.
Material and Methods:
This cross-sectional study, was done on 91 beta-thalassemia patients referring to the thalassemia center, Jahrom-Iran, 2021. Blood samples were collected from the patients and anti-HGV antibodies were evaluated by ELISA methods. Serum levels of ALT, AST, ALP and demographic data were extracted from patients' medical records. Descriptive analysis, X2, and T-test were used for statistical analyses by SPSS-16.
Results:
The prevalence anti-HGV IgG and IgM were 18.7 % and 5.5 %, respectively. There were significant relationships between the frequencies of anti-HGV antibodies and serum level of ALT, ASL, ALP and also with the history time of transfusion (P<0.05). But, there were no significant relationships between the frequencies of anti-HGV antibodies with patients' sex and the mean of age (P>0.05).
Conclusions:
HGV is one of the etiologic factors of hepatitis in thalassemia patients in Jahrom. Further comprehensive and molecular-based studies are recommended to explore the prevalence of HGV and its role in hepatitis thalassemia patients.
Keywords: Hepatitis G virus (HGV), Sero-prevalence, thalassemia, Iran
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Type of Study: Research | Subject: VirocShenaci
Received: 2021/10/30 | Revised: 2022/01/30 | Accepted: 2021/12/28
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Research code: IR.JUMS.REC.1399.086
Ethics code: IR.JUMS.REC.1399.086


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Shakeri M, rahmanian K, sotoodeh jahromi, sotoodeh jahromi A. Seroloprevalence of Hepatits G Virus (HGV) in Thalassemia Patients Jahrom-Iran, 1399. jmj 2021; 19 (3) :39-44
URL: http://jmj.jums.ac.ir/article-1-1662-en.html


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Volume 19, Issue 3 (fall 2021) Back to browse issues page
فصلنامه دانشگاه علوم پزشکی جهرم Journal of Jahrom University of Medical Sciences
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