Jahrom University of Medical Sciences Pars Journal of Medical Sciences 2717-0284 20 2 2022 08 23 Prevalence of natural acquired immunity to Streptococcus pneumoniae in hemodialysis patients Jahrom-Iran, 2022 Prevalence of natural acquired immunity to Streptococcus pneumoniae in hemodialysis patients Jahrom-Iran, 2022 48 54 700543 10.22034/pjms.2022.700543 FA Masihollah Shakeri Zoonosis Research Center, Jahrom University of medical sciences, Jahrom, Iran 0000-0001-9184-9912 Vahid Rahmanian Research Center for Social determinants of health, Jahrom University of medical sciences, Jahrom, Iran 0000-0003-3460-7495 Nona Hosseinnezhad Zoonoses Research center, Jahrom University of medical sciences, Jahrom, Iran. 0000-0001-9293-4158 Fatemeh Sotoodeh Jahromi Zoonoses Research center, Jahrom University of medical sciences, Jahrom, Iran 0000-0001-9293-4158 Abdolreza Sotoodeh Jahromi Zoonoses Research center, Jahrom University of medical sciences, Jahrom, Iran 0000-0002-2131-2113 Journal Article 2022 12 25 Introduction: Immune system disorders as one of the major problems in dialysis patients increase their susceptibility<br />to pneumococcal pneumonia. The present study was conducted for the first time in Iran with the aim of determining the prevalence of natural acquired immunity to Streptococcus pneumoniae in hemodialysis patients in Jahrom, Iran.<br />Material and Methods: This cross-sectional descriptive study was performed on 89 hemodialysis patients in Jahrom-Iran, 2022. The presence of anti-pneumococcal antibodies in the serum of patients was assessed by ELISA method. Demographic information, mean history of hemodialysis treatment and number of times per week were extracted from patients' records. Data were analyzed using SPSS Statistics-23 statistical software (IBM,USA) using descriptive statistics, chi-square and Fisher's exact test.<br />Results: The prevalence of immunity to Streptococcus pneumoniae in dialysis patients was 20.22%. There was a significant difference in the prevalence of pneumococcal immunity between participants in terms of age groups, sex and number of dialysis sessions per week (p<0.05) but there was no statistically significant relationship with the duration of dialysis treatment (p=0.09).<br />Conclusions: Prevalence of this type of immunity, which indicates a history of pneumococcal infection in dialysis patients in Jahrom. Due to the ability to prevent this infection by pneumococcal vaccination, the need for Iranian dialysis patients for pneumococcal vaccination is recommended. Introduction: Immune system disorders as one of the major problems in dialysis patients increase their susceptibility<br />to pneumococcal pneumonia. The present study was conducted for the first time in Iran with the aim of determining the prevalence of natural acquired immunity to Streptococcus pneumoniae in hemodialysis patients in Jahrom, Iran.<br />Material and Methods: This cross-sectional descriptive study was performed on 89 hemodialysis patients in Jahrom-Iran, 2022. The presence of anti-pneumococcal antibodies in the serum of patients was assessed by ELISA method. Demographic information, mean history of hemodialysis treatment and number of times per week were extracted from patients' records. Data were analyzed using SPSS Statistics-23 statistical software (IBM,USA) using descriptive statistics, chi-square and Fisher's exact test.<br />Results: The prevalence of immunity to Streptococcus pneumoniae in dialysis patients was 20.22%. There was a significant difference in the prevalence of pneumococcal immunity between participants in terms of age groups, sex and number of dialysis sessions per week (p<0.05) but there was no statistically significant relationship with the duration of dialysis treatment (p=0.09).<br />Conclusions: Prevalence of this type of immunity, which indicates a history of pneumococcal infection in dialysis patients in Jahrom. Due to the ability to prevent this infection by pneumococcal vaccination, the need for Iranian dialysis patients for pneumococcal vaccination is recommended. https://jmj.jums.ac.ir/article_700543_d8ce25705f8355e4fa96da10b0d0fede.pdf