Jahrom University of Medical Sciences Pars Journal of Medical Sciences 2717-0284 16 4 2022 12 25 Comparison of Aquatic Exercise Program and Vitamin D Supplementation on Vitamin D and hs-CRP Serum Levels in Children with Autism Spectrum Disorders Comparison of Aquatic Exercise Program and Vitamin D Supplementation on Vitamin D and hs-CRP Serum Levels in Children with Autism Spectrum Disorders 48 56 700401 10.52547/jmj.16.4.48 FA Soleyman Ansari Kolachahi PhD Student, Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, Iran 0000-0002-2414-571X Zahra Hojjati Zidashti Associate Professor, Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, Iran 0000-0002-7058-1416 Alireza Elmieh Assistant Professor, Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht Branch, Rasht, Iran 0000-0002-6266-0018 Elham Bidabadi Associate Professor, Department of child neurology, Guilan University of Medical Sciences, Rasht, Iran 0000-0002-1067-3335 Journal Article 2022 12 25 Introduction: Previous studies have shown that levels of vitamin D in children with autism spectrum disorder (ASD)<br />are lower than normal ones and it has a reverse relationship with hs-CRP serum levels. The purpose of this study was to compare the effect of two methods of vitamin D supplementation and aquatic exercise training on vitamin D and hs-CRP serum levels in children with ASD.<br />Materials and Methods: In this study, 30 boys with autism spectrum disorder in Rasht with an average age of 10.45 ± 2.83 were voluntarily selected and randomly divided into three groups of supplementation (N=10), aquatic exercise (N=10) and control groups (N=10). Participants in the supplementary group orally received vitamin D supplementation (50,000 units) for ten weeks, once a week. Aquatic exercise group received aquatic exercise training for ten weeks, 60 min/ 2 sessions per week. Serum levels of vitamin D and hs-CRP were measured before and after 10 weeks. For data analysis, ANCOVA was used at the level of p<0.05 and SPSS software, version 21 was utilized.<br />Results: Both ten weeks aquatic exercise and supplementary improved serum levels of his-CRP in children with autism (p <0.05); However, only vitamin D supplementation improved vitamin D serum levels (p <0.05) and aquatic exercise intervention had no significant effect on vitamin D levels.<br />Conclusion: Aquatic exercise and vitamin D supplementation, as low-cost therapies can reduce the level of hs-CRP and improve the serum level of vitamin D in children with ASD<br /><br /> Introduction: Previous studies have shown that levels of vitamin D in children with autism spectrum disorder (ASD)<br />are lower than normal ones and it has a reverse relationship with hs-CRP serum levels. The purpose of this study was to compare the effect of two methods of vitamin D supplementation and aquatic exercise training on vitamin D and hs-CRP serum levels in children with ASD.<br />Materials and Methods: In this study, 30 boys with autism spectrum disorder in Rasht with an average age of 10.45 ± 2.83 were voluntarily selected and randomly divided into three groups of supplementation (N=10), aquatic exercise (N=10) and control groups (N=10). Participants in the supplementary group orally received vitamin D supplementation (50,000 units) for ten weeks, once a week. Aquatic exercise group received aquatic exercise training for ten weeks, 60 min/ 2 sessions per week. Serum levels of vitamin D and hs-CRP were measured before and after 10 weeks. For data analysis, ANCOVA was used at the level of p<0.05 and SPSS software, version 21 was utilized.<br />Results: Both ten weeks aquatic exercise and supplementary improved serum levels of his-CRP in children with autism (p <0.05); However, only vitamin D supplementation improved vitamin D serum levels (p <0.05) and aquatic exercise intervention had no significant effect on vitamin D levels.<br />Conclusion: Aquatic exercise and vitamin D supplementation, as low-cost therapies can reduce the level of hs-CRP and improve the serum level of vitamin D in children with ASD<br /><br /> https://jmj.jums.ac.ir/article_700401_929d37d0bcff9a9c2d7dd74fe120b22e.pdf