Jahrom University of Medical Sciences Pars Journal of Medical Sciences 2717-0284 14 2 2022 12 25 Comparision of pulmonary function and pulmonary inflammation in professional mid-endurance female runners and Non-athletes Comparision of pulmonary function and pulmonary inflammation in professional mid-endurance female runners and Non-athletes 15 20 700327 10.29252/jmj.14.2.15 FA Leili Zeiaadini Dashtkhaki Seyed Mahmood Hejazi Mohammad Hosseinzadeh Mohsen Naser Exir Vizvari Journal Article 2022 12 25 Goals: There is a close and significant relationship between pulmonary functioning, and general health and death rate. With regard to the very limited number of research conducted in Iran on the pulmonary functioning of mid-endurance  Iranian woman athletes, this study aims at investigating the effects of physical activity on pulmonary function of professional mid-endurance female runners . Methodology: This semi-experimental study applied pre-test and post-test purposefully and voluntarily on 15 mid-endurance  Female  runners and 15 non-athletes. Pulmonary volumes were measured during, right after, and 10 minutes after Couper’s test. Half an hour later, a sample of the sputum was taken to check bronchia factors (p≥0.05). Findings: A significant intragroup FVC level was found (p<0.003), (p<0.000), but not a significant intergroup difference. Based on the 15% and more decrease in FEV1 following physical activity, bronchospasm frequency due to exercise was 6.66% in the athletes’ group and 13.33 % in non-athletes. No significant difference was found after a comparison of inflammatory leukocytes was run. Conclusion: The greatest difference was concerned with the FVC volume, being significant within each group. The average proportion of FEV1 to FVC in athletes and non-athletes, however, were reported 89% and 85%, respectively, which is suggestive of a better respiratory functioning in mid- endurance  woman athletes as compared to that in non-athlete women. Goals: There is a close and significant relationship between pulmonary functioning, and general health and death rate. With regard to the very limited number of research conducted in Iran on the pulmonary functioning of mid-endurance  Iranian woman athletes, this study aims at investigating the effects of physical activity on pulmonary function of professional mid-endurance female runners . Methodology: This semi-experimental study applied pre-test and post-test purposefully and voluntarily on 15 mid-endurance  Female  runners and 15 non-athletes. Pulmonary volumes were measured during, right after, and 10 minutes after Couper’s test. Half an hour later, a sample of the sputum was taken to check bronchia factors (p≥0.05). Findings: A significant intragroup FVC level was found (p<0.003), (p<0.000), but not a significant intergroup difference. Based on the 15% and more decrease in FEV1 following physical activity, bronchospasm frequency due to exercise was 6.66% in the athletes’ group and 13.33 % in non-athletes. No significant difference was found after a comparison of inflammatory leukocytes was run. Conclusion: The greatest difference was concerned with the FVC volume, being significant within each group. The average proportion of FEV1 to FVC in athletes and non-athletes, however, were reported 89% and 85%, respectively, which is suggestive of a better respiratory functioning in mid- endurance  woman athletes as compared to that in non-athlete women. https://jmj.jums.ac.ir/article_700327_6cd28300413d3e63178f0bf7e2130569.pdf