:: Volume 7, Issue 1 And 2 (spring&summer 2009) ::
jmj 2009, 7(1 And 2): 1-6 Back to browse issues page
بررسی اثر ضدالتهابی عصاره زردچوبه Curcuma longa در مدل تجربی التهاب حاد
Afsaneh Ranjbar *, Mohammad Ranjbar
Abstract:   (4009 Views)

Introduction: The use of turmeric derived from the rhizome of the curcuma longa for treatment of different inflammatory diseases has been described in traditional Chinese medicine for thousands of years. Therefore ,we decided to study anti - inflammatory effects of this plant in  an experimental inflammatory model.

 Materials and Methods:

The rhizome of the curcuma longa was prepared using percolation method. The paw edema of rats was induced by subcutaneous injection of 0.1 ml of 5% carrageenan . Assessment of the edema was performed by calculation of volume changes. Different doses of the extract (100/200/300 mg/Kg i.p)and ibuprofen (12mg/kg) were given ten minutes before injection of carrageenan

Results: The results indicated that  the increase of the volume was significantly inhibited by all doses of the extract (P<0/05).

Conclusion: The obtained results suggest that rhizome of this plant could inhibit acute inflammatory responses.

Keywords: Anti-Inflammatory, Curcuma Longa, Carrageenan
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Type of Study: Research | Subject: ect
Received: 2016/06/1 | Revised: 2018/03/4 | Accepted: 2016/06/1

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