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:: Volume 11, Issue 2 (summer2013 2013) ::
jmj 2013, 11(2): 29-35 Back to browse issues page
The comparison of estrogen metabolites between active and inactive postmenopausal women
Amirhossein Haghighi , Rouya Askari , Mahdi Hedayati , Asmae Damanpak
Abstract:   (12266 Views)
Introduction: Regular physical activity may alter estrogen metabolism. The aim of the present study was to compare estrogen metabolites between active and inactive postmenopausal women. Materials and Methods: 75 postmenopausal women were asked to fill in the Beck questionnaire. Based on the questionnaire scales, they were divided into two groups: active and inactive. Blood samples were taken in fasting state from all subjects and serum concentration of 2-hydroxyestron and 16-hydroxyestron metabolites and their ratios measured. Independent t-test was used for data analysis. Results: The results showed that 2-hydroxyestron metabolite level and 2-hydroxyestron/16-hydroxyestron ratio were significantly higher among active postmenopausal women than inactive postmenopausal women but 16-hydroxyestron metabolite level was significantly lower among active postmenopausal women than inactive postmenopausal women. Conclusion: It is concluded that long-term physical activity can reduce breast cancer risk in postmenopausal women through influencing the estrogen metabolites.
Keywords: Physical activity, Metabolites, Estrogen, Postmenopausal, Cancer
Full-Text [PDF 270 kb]   (1392 Downloads)    
Type of Study: Research |
Received: 2013/08/27 | Accepted: 2013/09/28 | Published: 2013/09/28
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Haghighi A, Askari R, Hedayati M, Damanpak A. The comparison of estrogen metabolites between active and inactive postmenopausal women. jmj. 2013; 11 (2) :29-35
URL: http://jmj.jums.ac.ir/article-1-190-en.html


Volume 11, Issue 2 (summer2013 2013) Back to browse issues page
فصلنامه دانشگاه علوم پزشکی جهرم Journal of Jahrom University of Medical Sciences
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