:: Volume 15, Issue 3 (fall 2017) ::
jmj 2017, 15(3): 42-48 Back to browse issues page
Antimicrobial activity of Oscillatoria cyanobacterum
Ali Salehzadeh Dr
Assistant Professor, Department of Biology, Rasht Branch, Islamic Azad University, Rasht, Iran
Abstract:   (1138 Views)
 
Background and aim: Due to the increase of bacterial resistance to common antibiotics, tendency towards using natural compounds with antimicrobial activity was increased. Mean while, many bacterial species show multi or pan-resistant phenotypes. Many of these multidrug resistant (MDR) bacteria can cause life-threatening infections, being a major concern both in the hospital and the community. Therefore, in this study, we investigated the antimicrobial properties of cyanobacteria Oscillatoria sp.
 
Methods: The antimicrobial effect of cyanobacteria of Oscillatoria in concentrations of 50 mg/ml was investigated. The antimicrobial properties of cyanobacteria extract supernatant using in well diffusion agar was investigated. Moreover the minimum inhibitory concentration (MIC) was performed against human pathogenic bacteria such as, S. aureus, B. subtilis, P. aeruginosa and E. coli.
 
Findings: We observed the highest antimicrobial activity against E. coli bacteria with inhibition zone a diameter of 24 mm and the lowest antibacterial effect against P.aeruginosa with inhibition zone a diameter 14mm. In addition, the minimum inhibitory concentration of Oscillatoria extract against E. coli and Pseudomonas was documented in 3/125 and 12/5 mg/mL respectively.
 
Conclusion: Our results indicated that the methanolic extract of Oscillatoria had the proper antimicrobial activity against human pathogens and this inhibiotion was dose-dependent.
 
Keywords: Oscillatoria, Human Pathogens, Antimicrobial activity, Well diffusion agar
 
Keywords: Keywords: Oscillatoria, Human Pathogens, Antimicrobial activity, Well diffusion agar
Full-Text [PDF 458 kb]   (345 Downloads)    
Type of Study: Research | Subject: Microbshensi
Received: 2017/09/20 | Accepted: 2018/01/29 | Published: 2018/02/17


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Volume 15, Issue 3 (fall 2017) Back to browse issues page