[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 17, Issue 4 (winter 2019) ::
jmj 2019, 17(4): 17-25 Back to browse issues page
The study of antibiotic resistance and biofilm formation of isolated bacteria from upper respiratory tract in adult patients in Shahid Bahonar Hospital of Kerman
Zakieh Seifoori , Nadia Kazemi Pour
Islamic Azad University
Abstract:   (514 Views)
Introduction: Upper respiratory tract infection is one of the most common bacterial infections in humans and the second reason for the high administration of antibiotics. The upward trend of antibiotic resistance in bacterial pathogens is a worldwide challenge. The aim of the present study was to evaluate antibiotic resistance and biofilm formation of isolated bacteria from the upper respiratory tract of adult patients admitted to Shahid Bahonar Hospital in Kerman.
Materials and Methods: In this study, 70 sub cultured specimens of respiratory were received from laboratory of Shahid Bahonar Hospital in Kerman during three months . Examination and identification was done by routine biochemical tests. The disc diffusion antibiotic susceptibility test was also performed. Next, the percentage of cell surface hydrophobicity was determined. The isolates with highest and lowest hydrophobicity were selected to study biofilm formation on glass and polypropylene surfaces on static and shake conditions.
Results: 59 bacterial strains were isolated, respectively as %37.28 Staphylococcus aureus., %20.33 Klebsiella pneumonia, %16.94 pseudomonas aeruginosa, %6.77 Escherichia coli, %5.08 Streptococcus pneumonia and %3.38 Citrobacter spp., Serratia marcescen, Proteus mirabilis and Corynebacterium diphtheria. Maximum resistance was related to amoxicillin and all the strains were sensitive to gentamicin. The results of biofilm formation on the selected surfaces indicated biofilm formation increasing on propylene surfaces with shake condition.
Conclusion: According to the results, there is a direct relationship between antibiotic resistance and biofilm formation potential of isolates. An effective program can be developed by evaluating antibiotics susceptibility patterns and new therapeutic methods.
Keywords: Upper respiratory tract infection, Antibiotic resistance, cell surface hydrophobicity, Biofilm.
Full-Text [PDF 683 kb]   (88 Downloads)    
Type of Study: Research | Subject: Microbshensi
Received: 2019/10/16 | Accepted: 2020/03/15 | Published: 2020/03/15
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Seifoori Z, kazemi Pour N. The study of antibiotic resistance and biofilm formation of isolated bacteria from upper respiratory tract in adult patients in Shahid Bahonar Hospital of Kerman. jmj. 2019; 17 (4) :17-25
URL: http://jmj.jums.ac.ir/article-1-1407-en.html


Volume 17, Issue 4 (winter 2019) Back to browse issues page
فصلنامه دانشگاه علوم پزشکی جهرم Journal of Jahrom University of Medical Sciences
Persian site map - English site map - Created in 0.06 seconds with 31 queries by YEKTAWEB 4162