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:: Volume 10, Number 1 (4-2012) ::
jjums 2012, 10(1): 26-32 Back to browse issues page
The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes
MohammadJavad Hoseinzadeh Attar, Hossein Hajianfar , Aahmad Bahonar, Kazem Mohamad, SeyedAli Keshavarz, MohammadHasan Entezari, Gholamreza Askari
Dept. of Nutrition, School of Public Health and Institute of Public Health and Researches, Tehran University of Medical Science, International Campus, Kish, Iran
Abstract:   (11961 Views)
Introduction: Visfatin is an adipocytokine secreted from adipose tissue and can lead to the occurrence of diabetes. Omega-3 can decrease lipid profile and prevent insulin resistance. In the present study, the effect of Omega-3 on the serum visfatin concentration was compared with placebo. Material and Methods: A total of 71 women with type II diabetes were randomly assigned to a group that administered Omega-3 capsules or control group. First, the study subjects filled in a questionnaire including age, height, weight, waist circumference, and hip circumference. In addition, blood samples were taken to do the blood tests. In the second step, the intervention was done for 8 weeks and then data on the aforementioned variables were collected. In the blood samples visfatin and lipid profiles (LDL: low density lipoprotein, HDL: high density lipoprotein, TG: triglyceride and cholesterol), glucose, and HbA1c were measured. Results: There was no significant difference in serum visfatin level between groups before the intervention (p=0.14). However, after the intervention, the mean serum visfatin level in the Omega-3 group was significantly (P<0.001) higher. In addition, the mean differences before and after the serum visfatin level showed a significant difference in both groups (P<0.001). Conclusion: The use of omega-3 can increase visfatin level and also improve the effect of insulin in patients with type 2 diabetes. According to the similar effects of insulin and visfatin, the use of Omega-3 by diabetic patients is recommended. Also, further studies are recommended to be conducted on his subject to confirm the results of this study.
Keywords: Omega 3 Fatty Acids, Visfatin, Type 2 Diabetes Mellitus
Full-Text [PDF 226 kb]   (880 Downloads)    
Type of Study: Research |
Received: 2013/04/23 | Accepted: 2013/04/23 | Published: 2013/04/23
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Hoseinzadeh Attar M, Hajianfar H, Bahonar A, Mohamad K, Keshavarz S, Entezari M et al . The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes. jjums. 2012; 10 (1) :26-32
URL: http://jmj.jums.ac.ir/article-1-79-en.html
Volume 10, Number 1 (4-2012) Back to browse issues page
فصلنامه دانشگاه علوم پزشکی جهرم Journal of Jahrom University of Medical Sciences
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