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:: Volume 11, Number 3 (fall 2013 2013) ::
jjums 2013, 11(3): 39-47 Back to browse issues page
Effect of exercise on sex-hormone in rats with polycystic ovary syndrome
Maryam Sadat miri , Nikseresht Asghar, Hojat Karimi, kargarJahromi Hossein, said sobhaniyan
Abstract:   (11979 Views)
Introduction: Weight gain and fat accumulation are the risk factors which lead to polycystic ovary syndrome. The aim of this study was to examine the effect of exercise intensity on sexual hormone changes in rats with polycystic ovary syndrome. Materials and Methods: 40 female Wistar rats (180±20mg) with 2 to 3 consecutive estrous cycles during12 to 14 days were selected. The first two groups were divided into control (n=30) and polycystic (n=30) that got sick by estradiol valerate injection after 60 days. The polycystic groups were divided into three groups of observer (n=30), experiment group1 (low-intensity exercise (n=30)) and experiment group 2 (moderate intensity exercise (n=30)). Exercises were performed in 6 sessions of 60 minutes per week for 8 weeks. The mice were anesthetized by injection of 5 ml of blood directly from the heart and the blood factors were measured through Elisa ANOVA and LSD samples were used for normal distributions and Kruskal-Wallis test for analysis of data that were not normally distributed. Results: Concentrations of FSH in experiment group1increased significantly compared to the control and observer groups. Also, free testosterone was significantly higher as compared to the observer group. FSH concentration in group 2 was higher as compared to the control and observer groups, and changes to LH, estrogen and androstenedion were not significant compared to the control group despite their increase. Conclusion: According to weight changes and sexual hormones (FSH and Androstenedion) exercise, especially with low intensity, may improve the symptoms of polycystic ovary syndrome.
Keywords: Exercise, Polycystic Ovarian Syndrome, Sex Hormone, Rats
Full-Text [PDF 391 kb]   (1200 Downloads)    
Type of Study: Research |
Received: 2013/12/14 | Accepted: 2013/12/14 | Published: 2013/12/14
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miri M S, Asghar N, Karimi H, Hossein K, sobhaniyan S. Effect of exercise on sex-hormone in rats with polycystic ovary syndrome. jjums. 2013; 11 (3) :39-47
URL: http://jmj.jums.ac.ir/article-1-258-en.html
Volume 11, Number 3 (fall 2013 2013) Back to browse issues page
فصلنامه دانشگاه علوم پزشکی جهرم Journal of Jahrom University of Medical Sciences
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